Question #26 explained
Which of the following drugs is an option for a bite wound where Pasturella multocida is a bacteria of concern?
NOTE: Pasturella multocida is a facultative anaerobic Gram negative bacterium that produces penicillinases which render most penicillins ineffective. It is commonly a concern with bite wounds. Addition of a beta-lactamase inhibitor (i.e., clavulanic acid or sulbactam) expands coverage of aminopenicillins (i.e., amoxicillin or ampicillin) to include this organism.
A. Ampicillin – INCORRECT
B. Penicillin – INCORRECT
C. Cephalexin – INCORRECT: like all cephalosporins, this drug is largely ineffective against anaerobic organisms
D. Amoxicillin-clavulanic acid – CORRECT: is generally considered the first-line drug for both human or animal bite wounds