Bugs and Drugs Practice Test

Question #9 explained

Which of the following is true when comparing the activity of piperacillin-tazobactam (Zosyn) to the activity of cefepime (Maxipime)?

A. Pip/taz covers Pseudomonas aeruginosa and cefepime does not – INCORRECT: both drugs have activity against this non-fermenting Gram negative rod

B. Pip/taz covers Enterococcus faecalis and cefepime does not – CORRECT: note that when cefepime is used with vancomycin, the vancomycin will provide coverage for Enterococcus

C. Pip/taz covers Bacteroides fragilis and cefepime does not – CORRECT: cefepime lacks any substantial anaerobic coverage

D. Pip/taz covers methicillin-sensitive Staphylococcus aureus (MSSA) and cefepime does not – INCORRECT: both drugs cover MSSA

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